The central canal of the spinal cord is a narrow, fluid-filled channel that runs the length of the spinal cord. It is located in the center of the gray matter (nerve tissue) of the spinal cord and is lined with ependymal cells that produce cerebrospinal fluid. The central canal plays an important role in the circulation of cerebrospinal fluid, which nourishes and protects the spinal cord and brain. It also helps to transport nutrients and waste products to and from the spinal cord cells. The central canal can constrict or dilate to regulate the flow of cerebrospinal fluid, and it also contains the cells and fibers that transmit sensory and motor information to and from the body. While the central canal may decrease in size during the course of human development, it remains an important component of the spinal cord throughout a person's life.
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